Located in the center of Historic Downtown Wilson, The Wilson Amtrak station serves the Carolinian (New York-Richmond-Raleigh-Charlotte) and Palmetto (New York-Washington, DC-Charleston-Savannah-Jacksonville-Orlando-Tampa-Miami) routes.

The Atlantic Coast Line Railroad built the Flemish style depot in 1924. Designed by A.M. Griffin, this one-story brick building sports Spanish terra cotta roof tiles and an umbrella canopy that stretches the length of the station.

 In 1999, a 19? by 10? mural for the station’s waiting room was completed. It was commissioned by the North Carolina Department of Transportation and painted by artist Michael Brown. The mural depicts 100 years of railroad history in Wilson.